Stir crumbs, sugar and margarine until well-blended; press onto bottom of 9-inch springform pan. Bake for 10 minutes.
FILLING
Increase oven temperature to 400℉.
Mix cottage cheese and cream cheese at medium speed on electric mixer until well blended. Blend in sugar, flour and vanilla. Add eggs, one at a time, mixing well after each addition.
Pour filling mixture over crust. Bake for 10 minutes, then reduce the heat to 250℉. Continue baking for 35 to 45 minutes. Loosen from rim of pan; cool before removing rim of pan.